Chronic kidney disease (CKD) is a precursor to End Stage Renal Disease (ESRD). ESRD occurs when the kidney’s are no longer functioning with buildup of toxins in the body. Other signs of ESRD include issues with electrolytes, build up of acid in the body, swelling due to decreased urination and salt retention. Symptoms of ESRD include nausea, vomiting, fatigue, decreased appetite, weight loss, impaired cognition, sleep disturbance, and change in taste. Once the kidneys progress to ESRD, patients require renal replacement therapy either in the form of dialysis or kidney transplant. Talk to your doctor if you have CKD and the ways you can reduce your risk of progression to ESRD.